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Scientific Innovation: Tools and Techniques

Medical treatments and other innovations are often possible only after decades of less-publicized progress in developing novel techniques for measurement and manipulation. We support this work understanding that future scientists will build on our progress.

Our Work

Grant 11/2017
$11,367,500

The Institute for Protein Design seeks to better predict protein properties, which could lead to helpful applications in both human and animal health, such as facilitating faster creation of antiviral therapies in the event of a pandemic outbreak.

Press 10/2018
from Discover Magazine

After revolutionizing the study of proteins — molecules that perform crucial tasks in every cell of every natural organism — David Baker is now engineering them from scratch to improve on nature.

This article features our grantee.

Grant 10/2018
$2,550,171

The Open Philanthropy Project recommended a grant of $2,550,171 to Duke University to support research to develop CRISPR-based epigenetic tools to interrogate thousands of regions of DNA, allowing for more nuanced studies of genomic regions.

Press 3/2018
from Bloomberg

Applications include a vaccine to protect against all strains of the flu, a system to break down gluten to help people with celiac disease, and proteins that help convert solar energy to fuel.

We have supported research in this area.

Grant 2/2018
$3,000,000

Expansion microscopy could make it possible to visualize neural cell connections at a much lower cost than is possible with existing technology, with potentially dramatic implications for a variety of sub-fields within brain research.

Press 1/2018
from Quanta Magazine

MIT neuroscientist Ed Boyden, our grantee, hopes to decode all of biology and achieve human enlightenment. But he also has his eye on the path that will get him to each goal.

Press 12/2017
from The New York Times

Advances have given researchers confidence to design proteins from scratch, starting with a task they want a protein to do and then figuring out the string of amino acids that would fold the right way.

This article features our grantee.

Press 8/2017
from Scientific American

Scientists are developing increasingly complicated microscopy systems to study cells, molecules and even atoms for signs of disease.

This work was driven by our grantee MIT.

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