Disease and premature death are a major source of suffering. Treatments now potentially within reach may extend the human healthspan and improve quality of life. We aim to support tractable and cost-effective research on the world’s most burdensome diseases, including heart disease, cancer, malaria, and others. In addition to the grants listed here, Open Philanthropy Scientific Research staff advises Good Ventures on research related to Alzheimer’s disease.

Our Work

Press 11/2018
from The Economist

Target Malaria carries the prospect of huge humanitarian gains. It’s carefully designed, supported by Open Phil and the Gates Foundation, being carried out under international scrutiny, and gaining political support and inspiring a generation of researchers.

Press 9/2019
from Engineers Without Borders USA

The development of refrigeration technologies and approaches could have enormous potential, improving the lives of millions of the poorest and most vulnerable people on the planet. Open Philanthropy’s support helped establish the Chill Challenge.

Grant 7/2019

The Open Philanthropy Project recommended a grant of $484,785 over two years to Project Peanut Butter to complete a randomized controlled trial (RCT) on the effects of reformulated ready-to-use therapeutic foods on cognitive functioning in children with severe acute malnutrition.

Grant 5/2019

The Open Philanthropy Project recommended $500,000 to Engineers Without Borders USA to support a competition to develop prototypes for refrigerators and ice-makers that could provide sustainable and affordable refrigeration for off-grid communities.

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Grant 4/2019

The Open Philanthropy Project recommended $495,000 to support the work of three scholars identified by the American Pain Society in collaboration with the Rita Allen Foundation as outstanding researchers in the fields of pain, neuroscience, anesthesiology and neurology.

Press 4/2019
from The Sacramento Bee

EicOsis cleared a key regulatory hurdle with the U.S. Food and Drug Administration and expects to launch human trials later this year. Open Philanthropy has invested in EicOsis.

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Grant 3/2019

The Open Philanthropy Project recommended a grant of $180,000 to the Yale University School of Medicine to support research on vascular permeability that could be helpful in developing treatments for both Alzheimer’s Disease and sepsis.

Grant 2/2019

The Open Philanthropy Project recommended a grant of $1,134,975 to the University Health Network, a Canadian research center affiliated with the University of Toronto, to support a randomized controlled trial investigating the efficacy of an intervention to reduce preterm birth in Malawi.