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Project Peanut Butter — Ready-to-Use Therapeutic Food RCT

Organization Name 
Award Date 
Grant Amount 
To conduct an RCT on the effects of reformulated ready-to-use therapeutic foods on cognitive functioning in children with severe acute malnutrition
Topic (focus area) 

Published: October 2016

Project Peanut Butter staff reviewed this page prior to publication.

The Open Philanthropy Project recommended a grant of $724,929 over three years to support Project Peanut Butter to run a randomized controlled trial (RCT) on the effect on cognitive development of reformulated ready-to-use therapeutic food (RUTF) with additional omega-3 fatty acids and decreased omega-6 fatty acids, compared to conventional RUTF.

RUTF is primarily used to treat young children in the developing world with severe acute malnutrition, and is generally deficient in omega-3s while being relatively high in omega-6s. Our decision to recommend this grant was based on our belief that there is a reasonable chance that increasing the ratio of omega-3 to omega-6 fatty acids in RUTF will have a positive effect on the cognitive development of treated children, and that a clear result in a large randomized trial would be fairly likely to make use of the lipid-rebalanced RUTF standard practice.