Many of the most impactful discoveries in the history of science have been novel, pathbreaking findings that enabled subsequent exploration of whole new areas. We aim to fund basic science that could end up playing that enabling role when we see it as neglected by other potential funders.

Our Work

Blog Post 4/2015

Research that achieves broadly applicable insights about biological processes and brings on many new promising directions for research is difficult to be assured of “results” in the sense of new clinical applications.

Press 10/2019
from Genetic Engineering & Biotechnology News

Scientists at Arizona State University’s Biodesign Institute we supported have identified more than 200,000 cancer neoantigens, which could feasibly lead to the development of broad-spectrum cancer vaccines, as well as tumor type-specific treatments or patient-personalized vaccines.

Press 9/2019
from Nature

In a small trial, drugs seemed to rejuvenate the body’s ‘epigenetic clock’, which tracks a person’s biological age. The research was conducted by UCLA’s Steve Horvath, whose work we have supported.

Grant 8/2019

Dr. Hayashi has been at the forefront of research into methods of causing induced pluripotent stem cells to develop into oocytes in mice.

Grant 7/2019

Dr. Zernicka-Goetz’s proposed research would focus on understanding the molecular processes by which a single cell gives rise to all of the cell types and organ/tissue structures that comprise a fully developed embryo.

placeholder image where no real cover image exists
Grant 6/2019

The Open Philanthropy Project recommended a grant of $304,000 to UC Berkeley to support research on the impact of removing some blood constituents on indicators of aging in humans, led by Dr. Irina Conboy.

Grant 4/2019

The Open Philanthropy Project recommended $1,170,000 to the Life Sciences Research Foundation to support six early-career investigators working on issues including Alzheimer’s disease, infectious disease dynamics, cross-species transmission of bird flu and other areas.

Grant 4/2019

UCLA Professor Steve Horvath and collaborators are pursuing experiments to try and understand how the “epigenetic clock” algorithm measures age, and whether changes to the related processes could have positive effects on aging.