London School of Hygiene and Tropical Medicine — TB Vaccine Modeling

Photo courtesy of London School of Hygiene and Tropical Medicine

Open Philanthropy recommended a grant of $197,429 to the London School of Hygiene and Tropical Medicine to support a modeling study assessing the health and economic impacts of the TB vaccine candidate VPM1002 when used as a prevention-of-disease vaccine in low‐ and middle‐income countries. This study, led by Professor Richard White, will seek to update existing TB vaccine models with current data to estimate the key outcomes and overall cost-effectiveness of various rollout scenarios.

This falls within our focus area of global health R&D.

Catalyst — Cage-free Campaigns

Photo courtesy of Catalyst

Open Philanthropy recommended a grant of $745,000 over three years to Catalyst to support its work on cage-free reforms in Thailand and other Association of Southeast Asian Nations (ASEAN) countries.

This follows our November 2022 support and falls within our focus area of farm animal welfare.

London Initiative for Safe AI — General Support (2025)

Image courtesy of LISA

Open Philanthropy recommended a grant of £1,268,000 (approximately $1,647,005 at the time of conversion) to the London Initiative for Safe AI (LISA) for general support. LISA is a U.K. registered charity and research center that works to advance education in AI safety, reduce the risks from uncontrolled or misused AI systems, and contribute to the safe development, use, and governance of AI. It does so by supporting and empowering the London AI safety community and providing infrastructural support for AI safety initiatives.

This follows our July 2024 support and falls within our focus area of Global Catastrophic Risks Capacity Building.

YIMBY Melbourne — General Support

Photo courtesy of Mathew Lynn

Open Philanthropy recommended a grant of $500,000 over two years to YIMBY Melbourne for general support. YIMBY Melbourne advocates for the reform of restrictive land use regulations throughout Australia that limit housing supply and drive up costs.

This grant was made through our Abundance & Growth Fund.

Pakistan Air Quality Initiative — Air Quality in Pakistan (2025)

Open Philanthropy recommended a contract of $200,000 over two years with Pakistan Air Quality Initiative to support research on air quality in Pakistan, convene gatherings of experts, and provide strategic advice.

This follows our January 2024 contract and falls within our focus area of Global Public Health Policy.

This project was supported through a contractor agreement. While we typically do not publish pages for contractor agreements, we occasionally opt to do so.

FAR AI — AI Field Building 

Open Philanthropy recommended a grant of $1,800,000 over two years to FAR AI to support FAR Futures, an initiative that consists of events, outreach activities, and other programs aimed at helping to build and coordinate the fields of AI safety research and governance.

This falls within our focus area of Global Catastrophic Risks Capacity Building.