• Focus Areas
    • Cause Selection
    • Global Health & Wellbeing
      • Effective Altruism Community Growth (Global Health and Wellbeing)
      • Farm Animal Welfare
      • Global Aid Policy
      • Global Health & Development
      • Scientific Research
      • South Asian Air Quality
    • Longtermism
      • Biosecurity & Pandemic Preparedness
      • Effective Altruism Community Growth (Longtermism)
      • Potential Risks from Advanced AI
    • Other Areas
      • Criminal Justice Reform
      • History of Philanthropy
      • Immigration Policy
      • Land Use Reform
      • Macroeconomic Stabilization Policy
  • Grants
  • Research & Updates
    • Research Reports
    • Blog Posts
    • Notable Lessons
    • In the News
  • About Us
    • Grantmaking Process
    • How to Apply for Funding
    • Team
    • Contact Us
    • Stay Updated
  • We’re hiring!
  • Focus Areas
    • Cause Selection
    • Global Health & Wellbeing
      • Effective Altruism Community Growth (Global Health and Wellbeing)
      • Farm Animal Welfare
      • Global Aid Policy
      • Global Health & Development
      • Scientific Research
      • South Asian Air Quality
    • Longtermism
      • Biosecurity & Pandemic Preparedness
      • Effective Altruism Community Growth (Longtermism)
      • Potential Risks from Advanced AI
    • Other Areas
      • Criminal Justice Reform
      • History of Philanthropy
      • Immigration Policy
      • Land Use Reform
      • Macroeconomic Stabilization Policy
  • Grants
  • Research & Updates
    • Research Reports
    • Blog Posts
    • Notable Lessons
    • In the News
  • About Us
    • Grantmaking Process
    • How to Apply for Funding
    • Team
    • Contact Us
    • Stay Updated
  • We’re hiring!

Duke University — CRISPR-Based Epigenome Editing Tools (Charles Gersbach)

Visit Grantee Site
  • Portfolio Area: Scientific Innovation: Tools and Techniques
  • Focus Area: Scientific Research
  • Organization Name: Duke University
  • Amount: $2,550,171

  • Award Date: October 2018

Table of Contents

    Grant Investigators: Chris Somerville and Heather Youngs

    This page was reviewed but not written by the grant investigators. Duke University staff also reviewed this page prior to publication.

    The Open Philanthropy Project recommended a grant of $2,550,171 over three years to Duke University to develop tools to apply epigenome editing to refine genome wide association studies (GWAS). The work will be led by Charles Gersbach, the Rooney Family Associate Professor of Biomedical Engineering. This funding will support research to develop CRISPR-based epigenetic tools to interrogate thousands of regions of DNA, allowing for more nuanced studies of genomic regions identified through GWAS. The grant will also fund testing and verification of the tools by identifying loci implicated in schizophrenia, a poorly understood disorder.

    This grant falls within our interest in funding scientific research, and specifically within our interest in developing tools and techniques.

    Related Items

    • Scientific Innovation: Tools and Techniques

      Purdue University — Preclinical Data Research (Douglas Brubaker)

      Open Philanthropy recommended a grant of $1,500,000 over five years to Purdue University to support research led by Dr. Douglas Brubaker on developing a computational model to translate...

      Read more
    • Scientific Innovation: Tools and Techniques

      University of Notre Dame — Nanopore Protein Sequencing (Gregory Timp) (2021)

      Open Philanthropy recommended a grant of $1,769,056 over two years to the University of Notre Dame to continue support for Dr. Gregory Timp’s work developing an instrument that...

      Read more
    • Scientific Innovation: Tools and Techniques

      University of California, Los Angeles — Social Science Genetic Association Consortium (2020)

      Open Philanthropy recommended a grant of $2,250,000 to the University of California, Los Angeles, to support the Social Science Genetic Association Consortium (SSGAC). Our understanding is that SSGAC...

      Read more
    Back to Grants Database
    Open Philanthropy
    Open Philanthropy
    • Careers
    • Press Kit
    • Governance
    • Privacy Policy
    • Stay Updated
    Mailing Address
    182 Howard Street #225
    San Francisco, CA 94105
    Email
    [email protected]
    Media Inquiries
    [email protected]
    Anonymous Feedback
    Feedback Form

    © Open Philanthropy 2022 This work is licensed under a Creative Commons Attribution-Noncommercial-Share-alike 4.0 International License. If you'd like to translate this content into another language, please get in touch!