Broad Institute — Pandemic Preemption System (Pardis Sabeti and Christian Happi)

The Sabeti lab uses computational methods and genomics to understand mechanisms of evolutionary adaptation in humans and pathogens. (Photo courtesy of the Broad Institute.)

Grant Investigators: Heather Youngs and Chris Somerville

This page was reviewed but not written by the grant investigators. Broad Institute staff also reviewed this page prior to publication.


Open Philanthropy recommended a grant of $1,000,000 to the Broad Institute of MIT and Harvard to support work on a pandemic preemption system, led by Pardis Sabeti and Christian Happi of Redeemer’s University in Nigeria. The pandemic preemption system will use advanced technologies for the early detection and rapid containment of viral infections in the developing world. Sabeti is the cofounder of Sherlock Biosciences and has worked extensively on the epidemiology and management of dangerous viral diseases in Africa.

This falls within our work on scientific research, specifically within our interest in science supporting biosecurity and pandemic preparedness.

Broad Institute — COVID-19 Diagnostic Testing (Stacey Gabriel)

With help from various groups and individuals, the Broad Institute converted a clinical processing lab into a large-scale COVID-19 testing facility in a matter of days. (Photo courtesy of the Broad Institute.)

Grant Investigators: Heather Youngs and Chris Somerville

This page was reviewed but not written by the grant investigators. Broad Institute staff also reviewed this page prior to publication.


Open Philanthropy recommended a grant of $925,000 to the Broad Institute to support research led by Stacey Gabriel on the development, validation, and clinical testing of COVID-19 diagnostic tests. The funding will allow the Broad Institute, in partnership with the Massachusetts Department of Public Health, Partners Healthcare, and other clinical sites, to increase capacity for COVID-19 diagnostic testing and conduct clinical tests for tens of thousands of patients.

This falls within our work on scientific research, specifically within our interest in science supporting biosecurity and pandemic preparedness.

Broad Institute — Genome Editing Research (Feng Zhang)

(Image courtesy of the Broad Institute.)

Grant Investigators: Chris Somerville and Heather Youngs

This page was reviewed but not written by the grant investigators. Broad Institute staff also reviewed this page prior to publication.


Open Philanthropy recommended a grant of $2,500,000 over three years to the Broad Institute to support exploratory research on new technologies for genome editing, led by Feng Zhang. Zhang is well-known for his research on the discovery and applications of CRISPR enzymes for genome editing, and plans to use these funds to support a series of experiments to try and discover better ways of getting CRISPR reagents into cells for gene therapy applications, and several other topics.

This falls within our work on scientific research, specifically within our interest in advancing transformative basic science.