Open Philanthropy recommended a grant of $2,500,000 over three years to the International Vaccine Institute (IVI) to support a phase I clinical trial of a conjugate vaccine for cholera. IVI will run the clinical trial in partnership with EuBiologics. The trial will be conducted in South Korea with a focus on safety and tolerability in humans, and will test different doses and formulations for the vaccine. This falls within our focus area of scientific research, and specifically within our interest in advancing human health and wellbeing. International Vaccines Institute — Schistosomiasis Vaccine Assessment Open Philanthropy recommended a grant of$140,000 over two years to the International Vaccines Institute (IVI) to support the assessment of the safety and efficacy of SchistoShield®, a promising schistosomiasis vaccine candidate. The assessment will be conducted by the Vaccine Against Schistosomiasis in Africa project, which is led by IVI. If safe and effective, the vaccine could be used in both humans and cattle, the latter of which contribute to the spread of the disease.

This falls within our work on scientific research, specifically within our interest in advancing human health and wellbeing.