University of Utah — Henipavirus Antivirals (2024)

Open Philanthropy recommended a grant of $427,900 over two years to the University of Utah to support research led by Professors Michael Kay and Debbie Eckert on developing D-peptide antivirals against henipaviruses with pandemic potential, such as Hendra and Nipah virus.

This grant was funded via our request for proposals through the Pandemic Antiviral Discovery Initiative.

This follows our October 2022 support and falls within our focus area of biosecurity and pandemic preparedness.

Harvard Animal Law & Policy Clinic — Global Farmed Animal Benchmark

Image courtesy of Harvard Animal Law & Policy Clinic

Open Philanthropy recommended a grant of $350,000 over two years to the Harvard Animal Law & Policy Clinic to support the development of a pilot Global Farmed Animal Benchmark, a report comparing legal protections for farm animals across countries.

This falls within our focus area of farm animal welfare.

To learn more about new approaches and strategies, we sometimes make “experimental grants”, which involve less vetting than our other grants. This is an experimental grant.

Palisade Research — General Support

Open Philanthropy recommended a grant of $1,680,000 to Palisade Research for general support. Palisade Research studies AI capabilities to better understand misuse risks from current systems, and how advances in hacking, deception, and persuasion will affect the risk of catastrophic AI outcomes.

This falls within our focus area of potential risks from advanced artificial intelligence.

The grant amount was updated in August 2024.

Yale University School of Medicine — Sepsis Treatment Preclinical Tests

Open Philanthropy recommended a grant of $50,000 to the Yale University School of Medicine to support preclinical tests on the potential of syndecan inhibition as a treatment for sepsis, led by Dr. Michael Simons. This research builds on Dr. Simons’ previous work, which found that a protein called syndecan-2 is necessary for the activity of the vascular endothelial growth factor (VEGF), another protein that can cause blood vessels to leak during severe infections. By blocking syndecan-2, researchers hope to prevent some of the dangerous complications of sepsis.

This falls within our focus area of scientific research.

UC Santa Barbara — LLM Use Case Database

Open Philanthropy recommended a grant of $133,402 to the University of California, Santa Barbara to support a project led by Professor William Wang to build a database and taxonomy of large language model (LLM) use cases. This is one of two grants we recently made to support this work.

This grant was funded via a request for proposals for projects studying and forecasting the real-world impacts of systems built from LLMs. This falls within our focus area of potential risks from advanced artificial intelligence.

University of Minnesota — Legal Automation Benchmark

Open Philanthropy recommended a grant of $74,132 to the University of Minnesota to support a project to develop benchmarks for assessing large language models’ capabilities in automating legal tasks, led by Assistant Professor Dongyeop Kang.

This grant was funded via a request for proposals for projects benchmarking LLM agents on consequential real-world tasks and falls within our focus area of potential risks from advanced artificial intelligence.