Open Philanthropy recommended a grant of $1,700,000 over two years to the Center for Open Science to support the development of a systematic benchmark assessing how effectively large language models (LLMs) can evaluate, replicate, and conduct scientific research.
Open Philanthropy recommended a grant of $1,071,000 over two years to the Forecasting Research Institute to support the creation of a panel of AI experts who will forecast developments in AI capabilities, adoption, economic impacts, and other topics.
Open Philanthropy recommended a grant of $8,000,000 over three years to the Clinton Health Access Initiative to support market shaping for sickle cell disease, with the goal of lowering prices and expanding access to diagnostics and treatments.
Open Philanthropy recommended a gift of $1,070,495 over four years to the University of Southern California to support a clinical trial of combination supplements that have been shown to significantly reduce pre-term birth in low- and middle-income countries.
Open Philanthropy recommended a grant of $6,530,000 over three years to the Council on Strategic Risks to support its work on biosecurity fellowships and policy, as well as general operations.
Open Philanthropy recommended two grants totaling $10,000,000 over two years to Vital Strategies to support the RESET Alcohol Initiative, a consortium of six organizations working to reduce harms from excessive alcohol consumption in low- and middle-income countries.
Open Philanthropy recommended a gift of $330,000 over two years to Stanford University to support a project led byProfessor Mark Davis to develop ahuman organoid system for investigating immunological mechanisms and testing vaccine efficacy.
Organoids are clusters of cells that are produced by inducing differentiation of stem cells into some or all of the various cell types that comprise specific types of tissues and organs in animals. In some cases, the cells in organoids also assemble in ways that mimic the morphology found in animals.
Open Philanthropy recommended a grant of $2,500,000 over two years to Novartis to support a Phase IIa challenge trial of a new drug, ED1048, for the treatment of cryptosporidiosis.
Cryptosporidiosis is caused by the Cryptosporidium parasite. The parasite is widespread globally and highly resistant to sanitizers used for cleaning drinking water. The disease can be fatal in small children, the elderly, and immunocompromised people.
Open Philanthropy recommended a grant of INR 20,401,514 (approximately $248,632 at the time of conversion) over two years to People For Animals Uttarakhand to support a farm animal welfare movement-building fellowship in collaboration with the Ahimsa Trust and Humane Society International India. This 10-month fellowship trains fellows and places them in farm animal welfare jobs and internships.
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