Center for Open Science — LLM Research Benchmark

Photo courtesy of the Center for Open Science

Open Philanthropy recommended a grant of $1,700,000 over two years to the Center for Open Science to support the development of a systematic benchmark assessing how effectively large language models (LLMs) can evaluate, replicate, and conduct scientific research.

This grant was funded via a request for proposals for projects benchmarking LLM agents on consequential real-world tasks. This falls within our focus area of potential risks from advanced artificial intelligence.

University of Southern California — Clinical Trial for Preterm Birth Supplements

Photo courtesy of Jeffrey Klausner

Open Philanthropy recommended a gift of $1,070,495 over four years to the University of Southern California to support a clinical trial of combination supplements that have been shown to significantly reduce pre-term birth in low- and middle-income countries.

This follows our March 2023 support and falls within our focus area of scientific research, specifically within our interest in advancing human health and wellbeing.

Stanford University — Immunology Project

Open Philanthropy recommended a gift of $330,000 over two years to Stanford University to support a project led by Professor Mark Davis to develop a human organoid system for investigating immunological mechanisms and testing vaccine efficacy. 

Organoids are clusters of cells that are produced by inducing differentiation of stem cells into some or all of the various cell types that comprise specific types of tissues and organs in animals. In some cases, the cells in organoids also assemble in ways that mimic the morphology found in animals.

This falls within our focus area of scientific research.

Novartis — Cryptosporidiosis Challenge Trial

Image courtesy of Novartis

Open Philanthropy recommended a grant of $2,500,000 over two years to Novartis to support a Phase IIa challenge trial of a new drug, ED1048, for the treatment of cryptosporidiosis.

Cryptosporidiosis is caused by the Cryptosporidium parasite. The parasite is widespread globally and highly resistant to sanitizers used for cleaning drinking water. The disease can be fatal in small children, the elderly, and immunocompromised people.

This falls within our focus area of scientific research.

People For Animals Uttarakhand — Farm Animal Welfare Fellowship (2024)

Photo courtesy of PFA Uttarakhand

Open Philanthropy recommended a grant of INR 20,401,514 (approximately $248,632 at the time of conversion) over two years to People For Animals Uttarakhand to support a farm animal welfare movement-building fellowship in collaboration with the Ahimsa Trust and Humane Society International India. This 10-month fellowship trains fellows and places them in farm animal welfare jobs and internships.

This follows our September 2023 support and falls within our focus area of farm animal welfare, specifically within our interest in farm animal welfare in Asia.